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Human lung exposomics analysis

ABSTRACT: We tested the general utility of XLE in a variety of human biological samples by analyzing human lung and thyroid tissues and stool samples. We quantified 32 environmental chemicals in 11 human lungs, with HCB, PCB-28 and PCB-18 being most frequently detected (10 out of 11). The commonly detected chemicals in human plasma were detected less frequently in the lung. For the 11 lungs, p,p’-DDE was detected in eight, PCB-153 in five, PBDE-47 and PCB-138 in four and PCB-180 in three. Although the plasma samples were from non-diseased individuals and the lungs were both diseased and non-diseased individuals, HCA results suggest that environmental chemical profiles in human lung may be very different from plasma.

ORGANISM(S): Human Homo Sapiens

TISSUE(S): Lung

SUBMITTER: Xin Hu

PROVIDER: ST001802 | MetabolomicsWorkbench | Thu May 06 00:00:00 BST 2021

REPOSITORIES: MetabolomicsWorkbench

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