Metabolomics

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A Sentinel Serum Quality Management Program for NMR Metabolomics


ABSTRACT: Pooled human serum (Sentinel Serum Samples) was aliquoted for storage at -80C and subsequently had NMR spectra acquired annually for three years. This was to determine sentinel serum sample utility for a quality management program to monitor NMR reproducibility. Sentinel serum quality control samples allowed the quantification of variance between different profilers within a project. They also demonstrated declines in metabolite concentrations over time. A sentinel program is useful for tracking changes in QC serum samples from long-term storage. Separately, QC samples show negligible variance introduced by multiple profilers of NMR spectra within a project.

ORGANISM(S): Human Homo Sapiens

TISSUE(S): Blood

SUBMITTER: Kathleen Stringer  

PROVIDER: ST002022 | MetabolomicsWorkbench | Tue Nov 30 00:00:00 GMT 2021

REPOSITORIES: MetabolomicsWorkbench

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