Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Scabies mite genome project

ABSTRACT: Genomic resources and draft reference assemblies of the human and porcine scabies mites, Sarcoptes scabiei var. hominis and var. suis

PROVIDER: PRJEB12428 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR1223401_1.fastq.gz	Fastqsanger.gz
	ERR1223401_2.fastq.gz	Fastqsanger.gz
	ERR1223402_1.fastq.gz	Fastqsanger.gz
	ERR1223402_2.fastq.gz	Fastqsanger.gz
	ERR1223484_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Sarcoptes scabiei ES proteomics

Project description:Background: The parasitic mite Sarcoptes scabiei is an economically highly significant parasite of the skin of humans and animals worldwide. This mite causes a neglected tropical disease (NTD), called scabies - one of the commonest dermatological problems globally, resulting in major morbidity, disability, stigma and poverty. In hyperendemic situations, scabies is often associated with secondary opportunistic bacterial infections/diseases - a major concern in children. Although some stages of this mite can be treated with drugs, resistance against some drugs is emerging, and there is no vaccine available against scabies. Here, we report molecular resources (including a high-quality genome as well as transcriptomic and proteomic data sets) for S. scabiei to aid basic and applied research of this and related mites.

2020-09-08 | PXD016925 | Pride

Transcriptome analysis of the host immune responses to Sarcoptes scabiei

Project description:Scabies is a human skin disease due to the burrowing ectoparasite Sarcoptes scabiei resulting in intense itching and inflammation and manifesting as skin allergy. Little is known about the specific scabies molecules and genes involved in the host inflammatory and immunologic responses. We interrogated the transcriptome profiles of skin biopsies using next generation sequencing and a combined clustering and pathway mapping approach which will enable us in the identification of key signaling events in the host immune and inflammatory responses to S. scabiei infestation. With the comprehensive analysis of RNA-seq results, it has been found that the immune response of host inhibits S. scabiei immune pathway, proliferation and metabolism signaling pathways, out of which the signaling pathway seems to be the main pathway in innate immune response of S. scabiei. The analysis of immune pathway, hydrolase and allergen will contribute to the research of S. scabiei pathogenesis, diagnosis and development of vaccines.

2021-06-22 | GSE178563 | GEO

Sarcoptes scabiei somatic proteomes

Project description:Presently, there is a dearth of proteomic data for parasitic mites and their relationship with the host animals. Here, using a high throughput LC-MS/MS-based approach, we undertook the first comprehensive, large-scale proteomic investigation of egg and adult female stages of the scabies mite, Sarcoptes scabiei – one of the most important parasitic mites of humans and other animals worldwide. In total, 1,761 S. scabiei proteins were identified and quantified with high confidence. Bioinformatic analyses revealed differentially expressed proteins to be involved predominantly in biological pathways or processes including genetic information processing, energy (oxidative phosphorylation), nucleotide, amino acid, carbohydrate and/or lipid metabolism, and some adaptive processes. These proteomic data set will enable future molecular, biochemical and physiological investigations of early developmental stages of S. scabiei and the discovery of novel interventions targeting the egg stage, given its non-susceptibility to current acaricidal treatments.

2022-11-11 | PXD032148 | Pride

Sarcoptes scabiei var. suis

Project description:Sarcoptes scabiei var. suis Raw sequence reads

| PRJNA513944 | ENA

Homo sapiens

Project description:Sarcoptes scabiei Mites Modulate Gene Expression In Human Skin Equivalents

| PRJNA210230 | ENA

Sarcoptes scabiei

Project description:Sarcoptes scabiei overview

| PRJNA298267 | ENA

E-GEOD-48459

Project description:Sarcoptes scabiei Mites Modulate Gene Expression In Human Skin Equivalents

2015-07-15 | E-GEOD-48459 | ExpressionAtlas

Sarcoptes scabiei Mites Modulate Gene Expression In Human Skin Equivalents

Project description:The purpose of this study was to identify genes in keratinocytes and fibroblasts in human skin equivalents that changed expression in response to the burrowing of live scabies mites.

2013-07-03 | GSE48459 | GEO

Sarcoptes scabiei

Project description:RNA seq and functional annotation of Sarcoptes scabiei var. nyctereutis

| PRJDB6658 | ENA

mite metagenome

Project description:Microbiome of mites

| PRJDB7276 | ENA