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Saccharomyces pastorianus SOLiD4 based resequencing

ABSTRACT: Whole genome resequencing of three Saccharomyces pastorianus strains using a SOLiD 4 sequencer resulting in 50bp single-end reads.

PROVIDER: PRJEB4654 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR348226.fastq.gz	Fastqsanger.gz
	ERR348227.fastq.gz	Fastqsanger.gz
	ERR348228.fastq.gz	Fastqsanger.gz

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Saccharomyces pastorianus SOLiD4 based resequencing

Project description:Whole genome resequencing of three Saccharomyces pastorianus strains using a SOLiD 4 sequencer resulting in 50bp single-end reads.

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Project description:We report the gene expression profile of two polypolid Saccharomyces pastorianus, lager yeast strains, the Group I strain CBS1538 and the Group II strain W34/70. Saccharomyces pastorianus is a hybrid of Saccharomuyces cerevisiaie and Saccharomyces eubayanus. We report that the gene expression patterns are correlated with the gene copy number of S. cerevisiae and S. eubayanus alleles.

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Project description:Saccharomyces pastorianus is a natural yeast evolved from different hybridisation events between the mesophilic S. cerevisiae and the cold-tolerant S. eubayanus. This complex aneuploid hybrid carries multiple copies of the parental alleles alongside specific hybrid genes and encodes for multiple protein isoforms which impart novel phenotypes, such as the strong ability to ferment at low temperature. These characteristics lead to agonistic competition for substrates and a plethora of biochemical activities, resulting in a unique cellular metabolism. Here, we investigated the transcriptional signature of the different orthologous alleles in S. pastorianus during temperature shifts.

2021-10-14 | E-MTAB-11009 | biostudies-arrayexpress

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