Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Drosophila melanogaster

ABSTRACT: Genome-wide maps of PARP-1-bound nucleosomes.

PROVIDER: PRJNA242505 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR1202000.fastq.gz	Fastqsanger.gz
	SRR1202001.fastq.gz	Fastqsanger.gz
	SRR1202002.fastq.gz	Fastqsanger.gz
	SRR1202003.fastq.gz	Fastqsanger.gz
	SRR1202004.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 5

Similar Datasets

Drosophila melanogaster

Project description:Genome-wide maps of HMGD1 and H1-bound nucleosomes.

| PRJNA214229 | ENA

Homo sapiens

Project description:Genome-wide maps of PARP-1-bound nucleosomes (human)

| PRJNA262735 | ENA

Drosophila melanogaster S2 cells nucleosome occupancy data after simulation by heat killed Staphylococcus aureus

Project description:The innate immune response is among the strongest genomic responses and is conserved across all metazoa. Although transcription during the innate immune response has been well studied, the associated chromatin reorganizations are largely uncharacterized. Here we show that Drosophila S2 cells stimulated with Staphylococcus aureus display a dynamic change in genome-wide nucleosome occupancy and sensitivity. We found a widespread and transient nucleosomal loss peaking at 30 minutes post stimulation, and we demonstrated that the regulatory potentials of nucleosomes differ following stimulation. In addition, we identified differentially sensitive nucleosomes with response-specific potentials. Our results provide high-resolution nucleosome-distribution maps of the fly genome, revealing chromatin's role in: the innate immune response to Gram-positive bacteria, response-specific regulatory-factor binding, and nucleosome sensitivity. We identify functional chromatin regulatory features associated with immune response, and lay a foundation for a framework linking general and locus-specific roles for nucleosomes in immune regulation. Drsophila S2 cells at 0hr, 30minutes, 1hr and 4hr post heat-killed Staphylococcus aureus stimulation

2015-02-28 | E-GEOD-66367 | biostudies-arrayexpress

Drosophila melanogaster S2 cells nucleosome occupancy data after simulation by heat killed Staphylococcus aureus

2015-02-28 | GSE66367 | GEO

Drosophila melanogaster

Project description:Genome-wide maps of GlcNAc bound proteins and Pho ChIP-seq in Drosophila S2 cells and pupae.

| PRJNA329506 | ENA

Drosophila melanogaster

Project description:Genome-wide maps of Yan chromatin association

| PRJNA148085 | ENA

Determinants of nucleosome organization in primary human cells

Project description:Genome-wide maps of nucleosome organization in human CD4+ T-cells, CD8+ T-cells, granulocytes, and from in vitro reconstitution. 8 samples include: nucleosome-bound DNA isolated from primary human CD4+ T-cells, nucleosome bound-DNA isolated from primary human CD8+ T-cells, nucleosome-bound DNA isolated from primary human granulocytes, nucleosome-bound DNA isoalted from in vitro reconstitution of nucleosomes with human genomic DNA, control DNA generated by micrococcal nuclease treatment of human genomic DNA, RNA-seq from human CD4+ T-cells, RNA-seq from human CD8+ T-cells, RNA-seq from human Granulocytes.

2011-04-19 | E-GEOD-25133 | biostudies-arrayexpress

Drosophila melanogaster

Project description:Genome-wide maps of KDM5 binding in drosophila adults

| PRJNA289118 | ENA

Drosophila melanogaster S2 cells nucleosome occupancy data after simulation by heat killed Salmonella typhimurium

Project description:In eukaryotes, nucleosomes participate in all DNA-templated events by regulating access to the underlying DNA sequence. However, the dynamics of nucleosomes during a genome response has not been well characterized . We stimulated Drosophila S2 cells with heat-killed Gram-negative bacteria Salmonella typhimurium, and mapped genome-wide nucleosome occupancy at high temporal resolution by MNase-seq using Illumina HiSeq 2500. We show widespread nucleosome occupancy change in S2 cells during the immune response, with the biggest nucleosomal loss occurring at 4hr post stimulation.

2014-12-24 | GSE64507 | GEO

Drosophila melanogaster

Project description:Genome-wide maps of CREB/CRTC binding in Drosophila mushroom body.

| PRJNA321666 | ENA