Mus musculus
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA267190 | ENA |
REPOSITORIES: ENA
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Project description:Changes of Cytokines and chemokines profiles were sucessfully determined between mouse non-treated vs LPS treated pregnant uteri using Qiagen PCR array. Pregnant mouse (FVB strain E8.5-9.5) were treated with LPS(2.5ug/mouse) or saline as control. 8h- or 16-h later, uteri tissues (N=3) were collected.
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Project description:Changes of Cytokines and chemokines profiles were sucessfully determined between mouse non-treated vs LPS treated pregnant uteri using Qiagen PCR array.
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2013-10-31 | GSE49980 | GEO
Project description:Located in the perisinusoidal space of Disse, hepatic stellate cells (HSCs) communicate with all other liver cell types by physical association and / or by producing cytokines and chemokines. In liver disease and folllowing liver transplantation, elevated levels of endotoxin (bacterial lipopolysaccharide: LPS) stimulate HSCs to produce increased amounts of cytokines and chemokines. Transcriptomic analysis of cultured HSCs stimulated with LPS yields a survey of expression changes which potentially modulate the hepatic inflammatory and immune responses. In two independent experiments, rat HSCs were cultured with or without 10 ng/ml LPS for 1h and 24h, then harvested for microarray analysis (i.e., 8 samples). In the first of these experiments, cells also were also harvested after 3, 6 and 12 hours of LPS treatment, for a total of 11 samples.
2013-10-31 | E-GEOD-49980 | biostudies-arrayexpress
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