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Moraxella catarrhalis

ABSTRACT: Moraxella catarrhalis Raw sequence reads

PROVIDER: PRJNA338378 | ENA |

REPOSITORIES: ENA

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Dataset's files

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			Action	DRS
	SRR4240461_1.fastq.gz	Fastqsanger.gz
	SRR4240461_2.fastq.gz	Fastqsanger.gz
	SRR4240473_1.fastq.gz	Fastqsanger.gz
	SRR4240473_2.fastq.gz	Fastqsanger.gz
	SRR4240474_1.fastq.gz	Fastqsanger.gz

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Gene Expression Profile of Moraxella catarrhalis Grown in Pooled Human Sputum

2014-02-02 | GSE27059 | GEO

Analysis of the Zur Regulon of Moraxella catarrhalis

Project description:This series of microarrays explores the genes regulated by the Zur gene of Moraxella catarrhalis.

2014-03-23 | GSE28151 | GEO

Gene Expression Profile of Moraxella catarrhalis Grown in Pooled Human Sputum

Project description:Comparison of the gene expression profile of Moraxella catarrhalis grown in the presence of 20% pooled human sputum in chemically-defined medium relative to Moraxella catarrhalis grown in chemically-defined medium alone. Moraxella catarrhalis ATCC43617 was grown to mid-logarithmic phase either in the presence of 20% pooled human sputum in chemically-defined medium or in chemically-defined medium alone. Total RNA was extracted from bacterial cells exposed to each of these conditions and cDNA was generated for CyDye labelling. 3 biologic replicates were generated and each replicate underwent a dye swap (total of 6 experimental data collections). The gene expression profile reported is that of Moraxella catarrhalis grown in the presence of pooled human sputum in a chemically-defined medium relative to Moraxella catarrhalis grown only in the presence of the chemically-defined medium.

2014-02-02 | E-GEOD-27059 | biostudies-arrayexpress

Characterization of the molecular interplay between Moraxella catarrhalis and human respiratory tract epithelial cells: Expression Moraxella catarrhalis strain BBH18 during adherence to human phanryngeal epithelial Detroit 562 cells

2013-06-27 | GSE47870 | GEO

Characterization of the molecular interplay between Moraxella catarrhalis and human respiratory tract epithelial cells: Expression response of human phanryngeal epithelial Detroit 562 cells to adherent Moraxella catarrhalis strain BBH18

2013-06-27 | GSE47711 | GEO

Moraxella catarrhalis

Project description:Moraxella catarrhalis Genome sequencing

| PRJNA688249 | ENA

Cytosolic immunity against Moraxella catarrhalis requires innate immune signalling pillars converging on inflammasome activation

Project description:RNA-sequencing of uninfected and Moraxella catarrhalis-infected bone marrow-derived macrophages (BMDMs) isolated from Ifnar1 knockout and wild-type mice.

2022-08-17 | GSE196164 | GEO

Moraxella catarrhalis

Project description:Moraxella catarrhalis Genome sequencing and assembly

| PRJNA297370 | ENA

Project description:During the course of infection, respiratory pathogens like Moraxella catarrhalis needs to adhere to epithelial cells of different host niches such as the nasopharynx and lungs. Consequently, efficient adhesion to epithelial cells is considered an important virulence trait of M. catarrhalis. We examined the interaction between human pharyngeal epithelial Detroit 562 cells and M. catarrhalis BBH18 during adherence using a combination of Tn-seq, a genome-wide negative selection screenings technology, and expression profiling of both host and pathogen. The results described in this study are further discussed in Stefan P.W. de Vries, Marc J. Eleveld, Peter W.M. Hermans, Hester J. Bootsma: Characterization of the molecular interplay between Moraxella catarrhalis and human respiratory tract epithelial cells, submitted. After 1 hour adherence to Detroit 562 cells, RNA was isolated from adherent (n = 4) and non-adherent (planktonic) (n = 4) M. catarrhalis BBH18 as well as from bacteria incubated in the infection medium alone (n = 3). RNA obtained from the adherent fraction was enriched for bacterial RNA using the MICROBEnrich kit (Ambion). Total RNA was labeled according to standard Nimblegen gene expression array protocols and hybridized to a 4x72K Nimblegen M. catarrhalis expression array for read-out.

2013-06-27 | E-GEOD-47870 | biostudies-arrayexpress

SWATH-MS proteome of Moraxella catarrhalis under iron restricted conditions

Project description:Moraxella catarrhalis is a human-restricted bacterial pathogen that causes otitis media in children and exacerbations of chronic obstructive pulmonary disease in adults. Iron is a co-factor required for the function of proteins involved in respiration and DNA replication, and thus is essential to life for most bacterial species. As iron is sequestered by host tissues, all host-adapted pathogens encounter periods of iron starvation. Previous studies have defined the repertoire of genes required for growth of M. catarrhalis under iron restricted conditions, and described differential expression at the transcriptional level. However, global changes in protein expression in response to iron starvation have not been investigated. Here we provide a SWATH-MS dataset describing differential expression of the M. catarrhalis CCRI-195ME proteome under iron restricted versus iron replete conditions.

2020-01-24 | PXD017206 | Pride

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