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Mus musculus

ABSTRACT: RNA-Sequencing and proteomics approaches reveal multi-cellular deficits in the cortex of Rett syndrome mice

OTHER RELATED OMICS DATASETS IN: PXD006460

PROVIDER: PRJNA379366 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR5349390.fastq.gz	Fastqsanger.gz
	SRR5349390_1.fastq.gz	Fastqsanger.gz
	SRR5349390_2.fastq.gz	Fastqsanger.gz
	SRR5349381_1.fastq.gz	Fastqsanger.gz
	SRR5349381_2.fastq.gz	Fastqsanger.gz

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Project description:Rett syndrome is an X-linked neurodevelopmental disorder caused by mutation in the methyl-CpG-binding protein 2 gene in the majority of cases. We describe an RNA sequencing dataset of postmortem brain tissue samples from four females clinically diagnosed with Rett syndrome and four age-matched female donors. The dataset contains transcriptomes from two brain regions, temporal and cingulate cortex, for each individual, providing a valuable resource to explore the biology of the human brain in Rett syndrome.

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