Project description:This dataset is provided in support of the identification of a collagen-degrading enzyme secreted by the fungus P. destructans. P. destructans is responsible for the disease white nose syndrome, which has infected and killed millions of North American bats. Our manuscript, titled "Destructin-1 is a Collagen-Degrading Endopeptidase Secreted by P. destructans, the Causative Agent of White-Nose Syndrome", is under review, and the data set will be released upon acceptance.
2015-03-23 | MSV000079085 | MassIVE
Project description:Sequencing of White-Nose Syndrome Pathogen
| PRJNA633856 | ENA
Project description:Host response to white-nose syndrome
Project description:This data is in support of a study entitled "Characterization of PdCP1, a Serine Carboxypeptidase from P. destructans, the Causal Agent of White-nose Syndrome" by Beekman, C. et al. which is submitted and under review. Data will be released upon acceptance of the publication.
2018-04-30 | MSV000082319 | MassIVE
Project description:Myotis myotis (greater mouse-eared bat) with white nose syndrome
Project description:We compared the proteomic profile of blood plasma in healthy and white-nose syndrome affected Myotis lucifugus in order to identify patho-physiological changes associated with the disease. Using two-dimensional gel electrophoresis and liquid chromatography-mass spectrometry we identified differentially expressed proteins for acute phase response, constitutive and adaptive immunity, oxidative stress defense, metabolism and structural proteins of exosomes and desmosomes, suggesting a systemic response against Pseudogymnoascus destructans infection in a North American bat species.