Project description:TAF4 directed immunoprecipitation of the the Pre-initiation complex from mouse embryonic stem cells with or without depletion of TATA-box binding protein (TBP).

2022-05-27 | MSV000089562 | MassIVE

MS data of the SFRP2 in mouse embryonic stem cell

Project description:detect SFRP2 interaction proteins in mouse embryonic stem cells

2023-11-15 | PXD046973 | iProX

Proteins interacting with Lnc530 in mouse embryonic stem cells

Project description:The goal of this study is to identify the potential interaction proteins of Lnc530 in mouse embryonic stem cells.

2023-02-12 | PXD040075 | iProX

Gene expression data of allodiploid embryonic stem cells.

Project description:RNA-Seq was used to assess the gene expression profiles of 4 allodiploid embryonic stem cell lines and 4 control embryonic stem cell lines. Moreover, single-cell RNA-Seq was used to quantify the transcriptomes of 87 allodiploid single cells.

2016-01-31 | GSE74533 | GEO

Gene expression data from embryonic stem cells

Project description:Understanding the identity of lineage-specific cells arising during manipulations of stem cells is necessary for developing their potential applications. For instance, replacement of crucial functions in organ failure by transplantation of suitable stem-cell-derived cells will be applicable to numerous disorders, but requires insights into the origin, function and fate of specific cell populations. We studied mechanisms by which the identity of differentiated cells arising from stem cells could be verified in the context of natural liver-specific stem cells and whether such differentiated cells could be effective for supporting the liver following cell therapy in a mouse model of drug-induced acute liver failure. By comparing the identity of naturally occurring fetal human liver stem cells, we found that cells arising in cultures of human embryonic stem cells (hESCs) recapitulated an early fetal stage of liver cells, which was characterized by conjoint meso-endoderm properties. Despite this fetal stage, hESC-derived cells could provide liver support with appropriate metabolic and ammonia-fixation functions, as well as cytoprotection, such that mice were rescued from acute liver failure. Therefore, spontaneous or induced differentiation of human embryonic stem cells along the hepatic endoderm will require transition through fetal-like stages. This offers opportunities to prospectively identify whether suitable cells have been generated through manipulation of stem cells for cell therapy and other applications. Gene expression was analyzed

2017-12-14 | GSE108048 | GEO

Expression data from lateral and paraxial mesodermal cells differentiated from mouse Embryonic Stem Cells

Project description:Expression data from lateral and paraxial mesodermal cells differentiated from mouse Embryonic Stem Cells

| PRJNA657174 | ENA