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FACS-sorted GFP-positive ureteric bud (UB) cells at postnatal day 0 (P0): wildtype (WT) vs. conditional Dot1-knockout (KO) from Hoxb7-positive cells

ABSTRACT: FACS-sorted GFP-positive ureteric bud (UB) cells at postnatal day 0 (P0): wildtype (WT) vs. conditional Dot1-knockout (KO) from Hoxb7-positive cells

PROVIDER: PRJNA434809 | ENA |

REPOSITORIES: ENA

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FACS-sorted GFP-positive ureteric bud (UB) cells at postnatal day 0 (P0): wildtype (WT) vs. conditional Dot1-knockout (KO) from Hoxb7-positive cells

Project description:Transcriptional profiling of GFP-positive UB cells from Hoxb7CreGFP mice without (WT) or with (KO) homozygously floxed DOT1 alleles at the age of postnatal 0. This experiment aimed to uncover the genome-wide alternation in gene expression resulting from the removal of DOT1 gene in the collecting duct cell population (Hoxb7 positive) and successive changes to the series of events in kidney development.

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miRNA expression data from embryonic ureteric bud (UB) cells

Project description:UB cells FACS sorted from E15.5 mouse kidneys were analyzed for miRNAs expression. E15.5 UB cells FACS sorted from Rosa26YFP; Hoxb7Cre mice, total RNAs including miRNAs were purified and used for miRNA microarray

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