Ophiostoma sp. PMI_507
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA572465 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Quorum sensing (QS) is a complex cell-cell communication mechanism that coordinates population-level behaviors in microbes. In eukaryotes, this phenomenon has been extensively described in the dimorphic yeast Candida albicans as its main QS molecule, the sesquiterpene alcohol farnesol, is responsible for various phenotypic (i.e., inhibition of yeast-to-hyphae transition, biofilm formation and, hence, pathogenesis) and metabolic (i.e., induction of oxidative stress and apoptosis) changes. Ophiostoma piceae CECT 20416 is a dimorphic saprotrophic ascomycete with biotechnological interest that also produces farnesol as a QS molecule, but in this case, the alcohol promotes the morphological transition to the mycelial form, biofilm formation, enzyme secretion, and melanin production. Here, we characterized the physiological response of Ophiostoma piceae to farnesol, and the molecular components of the QS system of this fungus have been investigated using a ‘multiomics’ approach that involved genomic, transcriptomic, and proteomic analyses. Some genes identified in this work are proposed as key factors in farnesol transport and signaling. We have also cataloged the genes undergoing major transcriptional changes triggered by the presence of the autoinducer, such as cell-wall remodeling, ROS protection, and melanin biosynthesis, using self-organizing maps (SOMs). This analysis could be useful for applications in the forestry industry, for enzyme production, and for the valorization of residues. Furthermore, it might as well help to investigate the QS mechanisms of clinically relevant fungi phylogenetically related to Ophiostoma.
2023-09-19 | GSE243253 | GEO
Project description:Ophiostoma ips strain:CBS 138721 Genome sequencing and assembly
| PRJNA403779 | ENA
Project description:Ophiostoma bicolor strain:3.2.9/KL Genome sequencing and assembly
| PRJNA358668 | ENA
Project description:Agaricomycetes sp. PMI_697 Standard Draft genome sequencing
| PRJNA364279 | ENA
Project description:Serendipita sp. 407 Standard Draft genome sequencing
| PRJNA443925 | ENA
Project description:Helotiales sp. PMI_846 Standard Draft genome sequencing
| PRJNA586371 | ENA
Project description:Oidiodendron sp. PMI_195 Standard Draft genome sequencing
| PRJNA586372 | ENA
Project description:Ilyonectria sp. PMI_658 Standard Draft genome sequencing
| PRJNA586374 | ENA