Qingda granules lower Angiotensin-II-induced blood pressure
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA695212 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR13559100_1.fastq.gz | Fastqsanger.gz | |||
| SRR13559100_2.fastq.gz | Fastqsanger.gz | |||
| SRR13559101_1.fastq.gz | Fastqsanger.gz | |||
| SRR13559101_2.fastq.gz | Fastqsanger.gz | |||
| SRR13559102_1.fastq.gz | Fastqsanger.gz |
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Project description:The goals of this study is to compare the differently expressed genes in renal tissue of C57BL/6 WT mice with or without Angiotensin II (AngII) treatment as well as differently expressed genes in the renal tissue of WT mice with AngII treatment with or without Qingda granule（QDG）treatment. The mice (n=15) were randomly divided into 3 groups: control, AngII,AngII+ QDG (n=5 for each group). Mice in Control and AngII groups were infused with saline or 500 ng/kg/min of AngII respectively, and intragastrically with double distilled water (dd H2O); while mice in AngII + QDG groups were infused with AngII (500 ng/kg/min) and intragastrically with 1.145 g/kg/D of QDG for 4 weeks. Then the renal tissue were used to identify differentially expressed genes among different groups.
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