Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Dirofilaria immitis and associated symbionts

ABSTRACT: Metagenome data from dog heart sample

PROVIDER: PRJNA723804 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR14299255_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

Circulating Dirofilaria immitis microRNAs in dog plasma

Project description:We report the presence of circulating miRNAs released by the filarial nematode Dirofilaria immitis into the host (Canis familiaris) bloodstream. MiRNA deep-sequencing combined with bioinformatics revealed over 200 mature miRNA sequences of potential nematode origin in Dirofilaria immitis-infected dog plasma in two independent analyses

2014-10-03 | E-GEOD-60170 | biostudies-arrayexpress

Dirofilaria immitis

Project description:Dirofilaria immitis Transcriptome or Gene expression

| PRJNA263509 | ENA

Dirofilaria immitis

Project description:Dirofilaria immitis exhibits sex- and stage-specific differences in excretory/secretory miRNA profiles in vitro

| PRJNA335393 | ENA

Dirofilaria immitis

Project description:Dirofilaria immitis Genome sequencing and assembly

| PRJNA588995 | ENA

Dirofilaria immitis

Project description:Dirofilaria immitis Transcriptome or Gene expression

| PRJNA80937 | ENA

Dirofilaria immitis

Project description:Dirofilaria immitis overview

| PRJNA69947 | ENA

Dirofilaria immitis

Project description:MicroRNA discovery and analysis of Dirofilaria immitis by deep sequencing.

| PRJNA152503 | ENA

Dirofilaria immitis

Project description:Tissue-Specific Transcriptomics and Proteomics of a Filarial Nematode and its Wolbachia Endosymbiont

| PRJNA281132 | ENA

Circulating Dirofilaria immitis microRNAs in dog plasma

Project description:We report the presence of circulating miRNAs released by the filarial nematode Dirofilaria immitis into the host (Canis familiaris) bloodstream.

2014-10-03 | GSE60170 | GEO

ABC-B transporter genes in Dirofilaria immitis.

Project description:Dirofilaria immitis is a filarial nematode causing infection and heartworm disease in dogs and other canids, cats, and occasionally in humans. Prevention with macrocyclic lactones (ML) is recommended during the mosquito transmission season. Recently, ML resistance has been reported. ABC-B transporter genes are thought to be involved in the mechanism of ML resistance in other nematodes. This study aimed to identify all the ABC-B transporter genes in D. immitis using as a reference the nDi.2.2 D. immitis whole genome, which is not completely annotated. Using bioinformatic tools and PCR amplification on pooled D. immitis genomic DNA and on pooled cDNA, nine ABC transporter genes including one pseudogene were characterized. Bioinformatic and phylogenetic analyses allowed identification of three P-glycoproteins (Pgps) (Dim-pgp-3 Dim-pgp-10, Dim-pgp-11), of two ABC-B half transporter genes (one ortholog of Cel-haf-4 and Cel-haf-9; and one ortholog of Cel-haf-1 and Cel-haf-3), of one ABC half transporter gene (ortholog of Cel-haf-5) that contained an ABC-C motif, and of one additional half transporter that would require functional study for characterization. The number of ABC-B transporter genes identified was lower than in Caenorhabditis elegans and Haemonchus contortus. Further studies are needed to understand their possible role in ML resistance in D. immitis. These ABC transporters constitute a base for ML resistance investigation in D. immitis and advance our understanding of the molecular biology of this parasite.

| S-EPMC4919315 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data