Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: VD3 mitigate salmonellosis

PROVIDER: PRJNA759703 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR15694074_1.fastq.gz	Fastqsanger.gz
	SRR15694074_2.fastq.gz	Fastqsanger.gz
	SRR15694075_1.fastq.gz	Fastqsanger.gz
	SRR15694075_2.fastq.gz	Fastqsanger.gz
	SRR15694076_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 46

Similar Datasets

VD3-VDR axis regulates the homeostasis and function of alveolar macrophage [ChIP-Seq]

Project description:Purpose: To understand the regulation of gene expression of alveolar macrophages by VD3-VDR axis

2019-01-08 | GSE124722 | GEO

Analysis of the cellular effect of 1α,25-dihydroxyvitamin D3 on lung NCI-H441 cells

Project description:Low serum levels or deficiency of 1α,25-dihydroxyvitamin D3 (VD3) are associated with a higher mortality in trauma patients with sepsis or acute respiratory distress syndrome, although the molecular mechanisms behind this observation are not yet understood. VD3 is known to stimulate lung maturity, alveolar type II cell differentiation and pulmonary surfactant synthesis. This study aims to expand the knowledge by quantitative characterization of NCI-H441 cells upon VD3 treatment at the proteome level.

2023-05-10 | PXD040622 | Pride

Transcriptome of ESCs upon VD3 treatment (+/-) MLL1 inhibition

Project description:This study describes the transcriptome profiling of: 1) Mll1fl/fl mESCs in LIF/Serum medium as control; 2) VD3 and MM-401 (Mll1i) treated mESCs in LIF/serum medium ; 2) VD3 treated mESCs in LIF/serum medium.

2019-12-02 | GSE131297 | GEO

VD3-VDR axis regulates the homeostasis and function of alveolar macrophage [RNA-Seq]

Project description:Purpose: To understand the regulation of gene expression of alveolar macrophages by VD3-VDR axis

2019-01-08 | GSE124724 | GEO

VD3-VDR axis regulates the homeostasis and function of alveolar macrophage [RNA-Seq LPS]

Project description:Purpose: To understand the regulation of gene expression of alveolar macrophages by VD3-VDR axis

2019-01-08 | GSE124723 | GEO

Transcription profiling of blood from HIV positive adults with non-typhoidal salmonellosis

Project description:To gain insight into the role of Non-typhoidal salmonellosis in HIV positive adults

2010-06-25 | E-TABM-856 | biostudies-arrayexpress

Vitamin D3 affects TNFa mediated activation of dendritic cells

Project description:The ability of dendritic cells (DC) to initiate immunity and induce antigen-specific tolerance makes DC ideal targets for pharmacological intervention into immune responses. NF-kB factors are a family of transcriptional regulators important for DC development and function. However, the identity of NF-kB target genes that are central to DC biology is largely unknown. In the present study inhibition of the NF-kB activation by the IkBa super repressor (IkBa-SR) and DNA microarray analysis were used to determine the repertoire of NF-kB responsive genes in DC. A number of immunomodulatory compounds have been suggested to target the NF-kB signalling pathway and/or NF-kB-mediated transcription of pro-inflammatory target genes. 1a,25-dihydroxyvitamin D3 (VD3) exerts its effects through the vitamin D3 receptor (VDR), a member of the nuclear hormone receptor superfamily. Microarray analysis was also selected as an approach of choice for the analysis of the effects of VD3 on the activation of DC, and to survey the involvement of VDR in repression of NF-kB regulated genes. These genes can be potentially useful targets for the development of more specific anti-inflammatory agents for clinical applications. Keywords: drug treatment, TNFa treatment, VD3 treatment DC were generated in vitro from bone marrow cells of VDRmut and VDRwt control mice as described previously (Hieronymus, T., T. C. Gust, R. D. Kirsch, T. Jorgas, G. Blendinger, M. Goncharenko, K. Supplitt, S. Rose-John, A. M. Muller, and M. Zenke. 2005. Progressive and controlled development of mouse dendritic cells from Flt3+CD11b+ progenitors in vitro. J Immunol 174:2552-2562). Immature DC were pre-treated with 1a,25-dihydroxyvitamin D3 (VD3), or left untreated. TNFa was added where appropriate, and cells incubated further for 4 h. Total RNA was amplified, labelled and hybridised to Affymetrix MOE430A arrays. TNFa up- and down-regulated genes, as well as genes affected by VD3 were analysed.

2012-12-31 | E-GEOD-8334 | biostudies-arrayexpress

RNA sequencing of enterocytes differentiated from human iPS cells

Project description:Our RNA-seq results showed that valproic acid (VPA) works synergistically with activated Vitamin D3 (VD3) to enhance the expression of enterocyte-function-related genes in iPS-derived enterocyte-like cells.

2023-05-25 | GSE226851 | GEO

miRNA_seq_Salmonella_pig

Project description:Salmonella enterica serovar Typhimurium is a gram-negative bacterium that can colonize the gut of humans and several species of food producing farm animals to cause enteric or septicaemic salmonellosis. Besides compromising public health and food safety, sub-clinical salmonellosis is also believed to be a major problem affecting the profitability of the pig industry. Distinct responses to Salmonella infection have been observed in pigs, some recovering faster and shedding lower levels of Salmonella in faeces than others (low shedders, LS versus persistent shedders, PS). This trait variation could indicate the existence of a genetic component to Salmonella shedding and resistance that may be exploited in animal breeding and disease diagnostics. The study aimed to characterize changes in miRNA expression in response to Salmonella infection.

2015-10-22 | E-MTAB-2286 | biostudies-arrayexpress

Salmonellosis surveillance in the EU/EEA

Project description:Salmonellosis surveillance in the EU/EEA

| PRJEB39132 | ENA