Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Enrichment and single-cell sequencing of the ventricular cells from zebrafish telencephalon

ABSTRACT: Enrichment and single-cell sequencing of the ventricular cells from zebrafish telencephalon

PROVIDER: PRJNA776627 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Enrichment and single-cell sequencing of the ventricular cells from zebrafish telencephalon

Project description:Zebfrafish brains were injected with neutral cell tracking dye. Zebrafish telencephalon were dissociated and dye postive cells were sorted by FACS and single-cell sequencing performed from these cells.

2022-06-24 | GSE186874 | GEO

A single-cell transcriptome atlas of the zebrafish telencephalon

Project description:Wild-type zebrafish telencephalon single-cell RNA-sequencing from 6 dpf, 15 dpf, and adult.

2022-09-02 | GSE212314 | GEO

Single-cell sequencing of 12 months old zebrafish telencephalon

2021-09-23 | GSE161834 | GEO

Single-cell sequencing of 12 months old zebrafish telencephalon

Project description:Single-cell sequencing of 12 months old zebrafish telencephalon

| PRJNA679600 | ENA

Single-cell transcriptome profiling of radial glia cells in zebrafish adult telencephalon in response to traumatic brain injury

Project description:In zebrafish brain, radial glia cells (RG) show a remarkable ability to regenerate damaged neural tissue by reentering cell proliferation and produce neural precursors. To understand how RG respond to brain damage and initiate the regenerative response, we applied single-cell transcriptome analysis to RG in zebrafish adult telencephalon.

2024-07-22 | GSE209705 | GEO

Granulins Regulate Aging Kinetics in the Adult Zebrafish Telencephalon

Project description:Granulins (GRN) are secreted factors that promote neuronal survival and regulate inflammation in various pathological conditions. However, their roles in physiological conditions in the brain remain poorly understood. To address this knowledge gap, we analysed the telencephalon in Grn-deficient zebrafish and identified morphological and transcriptional changes in microglial cells, indicative of a pro-inflammatory phenotype in the absence of any insult. Unexpectedly, activated mutant microglia shared part of their transcriptional signature with aged human microglia. Furthermore, transcriptome profiles of the entire telencephali isolated from young Grn-deficient animals showed remarkable similarities with the profiles of the telencephali isolated from aged wildtype animals. Additionally, 50% of differentially regulated genes during aging were regulated in the telencephalon of young Grn-deficient animals compared to their wildtype littermates. Importantly, the telencephalon transcriptome in young Grn-deficent animals changed only mildly with aging, further suggesting premature aging of Grn-deficient brain. Indeed, Grn loss led to decreased neurogenesis and oligodendrogenesis, and to shortening of telomeres at young ages, to an extent comparable to that observed during aging. Altogether, our data demonstrate a role of Grn in regulating aging kinetics in the zebrafish telencephalon, thus providing a valuable tool for the development of new therapeutic approaches to treat age-associated pathologies.

2020-02-18 | GSE144543 | GEO

Microarray analysis in the zebrafish liver and telencephalon after exposure to low concentration of 17a-EE2

Project description:Experiment exposed adult male zebrafish to 10ng/L 17-alpha ethinylestradiol for three weeks. Gene expression profiling of liver and telencephalon following exposure. Keywords: estrogenic exposure

2007-03-31 | GSE7220 | GEO

Wound healing process after ventricular resection in zebrafish: time course (zebrafish)

Project description:The mechanism of cardiomyocyte prliferation and migration after ventricular resection is a complex and dynamic process. To resolve this, we chose the zebrafish model organism for studying post-injury heart regeneration and wound healing progress via systems biology approach. Transcriptome microarray data and histological analysis of injured fish were sampled at different time points during recovery process. Time-course microarray data following wound healing of zebrafish were obatined. From this set of data, we constructed two intracellular protein–protein interaction (PPI) networks to provide insights into the ventricular resection wound healing mechanism.

2018-04-02 | GSE72348 | GEO

Granulins Regulate Aging Kinetics in the Adult Zebrafish Telencephalon

Project description:Granulins Regulate Aging Kinetics in the Adult Zebrafish Telencephalon

| PRJNA603998 | ENA

Comparative transcriptome analysis of the three different stages of the regenerating zebrafish telencephalon

Project description:Adult zebrafish can completely regenerate a wide range of injured organs including the CNS. RNA sequencing (RNA-Seq) is a high-throughput sequencing method facilitating quantification of gene expression in a precisely manner. Development of RNA-Seq technologies and their extensive data-analysis methods make investigation of regulatory genes and functional gene annotations possible under specific conditions. In this study, we reveal the whole transcriptome profiles of the lesioned hemispheres of the zebrafish telencephalon at early wound healing (1 day post-lesion), early proliferative (3 day post-lesion) and differentiation (14 day post-lesion) stages of regeneration.

2022-01-31 | E-MTAB-11163 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data