Proteomics,Multiomics

Dataset Information

0

IMR90_iPS_BioReplica_02_ETD


ABSTRACT: Hs iPS_vs_HES - IMR90_iPS_BioReplica_02 ETD

OTHER RELATED OMICS DATASETS IN: PXD000134PRJNA136559PRJNA142175PRJNA142177

INSTRUMENT(S): LTQ Orbitrap XL

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Others

SUBMITTER: Munoz J, Low TY, Kok YJ, Chin A, Frese CK, Ding V, Choo A, Heck AJ 

PROVIDER: PAe004086 | PeptideAtlas | 2011-12-31

REPOSITORIES: PeptideAtlas

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Publications

The quantitative proteomes of human-induced pluripotent stem cells and embryonic stem cells.

Munoz Javier J   Low Teck Y TY   Kok Yee J YJ   Chin Angela A   Frese Christian K CK   Ding Vanessa V   Choo Andre A   Heck Albert J R AJ  

Molecular systems biology 20111122


Assessing relevant molecular differences between human-induced pluripotent stem cells (hiPSCs) and human embryonic stem cells (hESCs) is important, given that such differences may impact their potential therapeutic use. Controversy surrounds recent gene expression studies comparing hiPSCs and hESCs. Here, we present an in-depth quantitative mass spectrometry-based analysis of hESCs, two different hiPSCs and their precursor fibroblast cell lines. Our comparisons confirmed the high similarity of h  ...[more]

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