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Hs_Glioblastoma

ABSTRACT: Accessibilome of Human Glioblastoma

REANALYSIS of: PXD001398

INSTRUMENT(S): BrukerDaltonics amaZon ion trap

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Brain

SUBMITTER: Turtoi A, Blomme A, Bianchi E, Maris P, Vannozzi R, Naccarato AG, Delvenne P, De Pauw E, Bevilacqua G, Castronovo V

PROVIDER: PAe005158 | PeptideAtlas | 2014-12-31

REPOSITORIES: PeptideAtlas

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Publications

Accessibilome of human glioblastoma: collagen-VI-alpha-1 is a new target and a marker of poor outcome.

Turtoi Andrei A Blomme Arnaud A Bianchi Elettra E Maris Pamela P Vannozzi Riccardo R Naccarato Antonio Giuseppe AG Delvenne Philippe P De Pauw Edwin E Bevilacqua Generoso G Castronovo Vincent V

Journal of proteome research 20141103 12

Functional targeted therapy has unfortunately failed to improve the outcome of glioblastoma patients. Success stories evidenced by the use of antibody-drug conjugates in other tumor types are encouraging, but targets specific to glioblastoma and accessible through the bloodstream remain scarce. In the current work, we have identified and characterized novel and accessible proteins using an innovative proteomic approach on six human glioblastomas; the corresponding data have been deposited in the ...[more]

PMID: 25325876

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