Dataset Information

Characterization of the Mouse Brain Proteome Using Global Proteomic Analysis Complemented with Cysteinyl-Peptide Enrichment

ABSTRACT: Whole Mouse brain proteome analysis.

INSTRUMENT(S): instrument model, LTQ

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Brain

SUBMITTER: DAVE THORNEYCROFT

PROVIDER: PRD000010 | Pride | 2006-01-24

REPOSITORIES: pride

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Dataset's files

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			Action	DRS
	PRIDE_Exp_Complete_Ac_1637.pride.mztab.gz	Mztab
	PRIDE_Exp_Complete_Ac_1637.xml.gz	Xml
	PRIDE_Exp_Complete_Ac_1638.pride.mztab.gz	Mztab
	PRIDE_Exp_Complete_Ac_1638.xml.gz	Xml
	PRIDE_Exp_Complete_Ac_1639.pride.mztab.gz	Mztab

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Publications

Characterization of the mouse brain proteome using global proteomic analysis complemented with cysteinyl-peptide enrichment.

Wang Haixing H Qian Wei-Jun WJ Chin Mark H MH Petyuk Vladislav A VA Barry Richard C RC Liu Tao T Gritsenko Marina A MA Mottaz Heather M HM Moore Ronald J RJ Camp Ii David G DG Khan Arshad H AH Smith Desmond J DJ Smith Richard D RD

Journal of proteome research 20060201 2

We report a global proteomic approach for analyzing brain tissue and for the first time a comprehensive characterization of the whole mouse brain proteome. Preparation of the whole brain sample incorporated a highly efficient cysteinyl-peptide enrichment (CPE) technique to complement a global enzymatic digestion method. Both the global and the cysteinyl-enriched peptide samples were analyzed by SCX fractionation coupled with reversed phase LC-MS/MS analysis. A total of 48,328 different peptides ...[more]

PMID: 16457602

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