Proteomics

Dataset Information

0

Platelet membrane proteomics - Platelet membrane proteomics: a novel repository for functional research


ABSTRACT: Not available

INSTRUMENT(S): instrument model, QSTAR

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Platelet

SUBMITTER: Steffi Wortelkamp  

PROVIDER: PRD000068 | Pride | 2009-08-24

REPOSITORIES: Pride

Dataset's files

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Publications

Platelet membrane proteomics: a novel repository for functional research.

Lewandrowski Urs U   Wortelkamp Stefanie S   Lohrig Katharina K   Zahedi RenĂ© P RP   Wolters Dirk A DA   Walter Ulrich U   Sickmann Albert A  

Blood 20090512 1


Being central players in thrombosis and hemostasis, platelets react in manifold and complex ways to extracellular stimuli. Cell-matrix and cell-cell interactions are mandatory for initial adhesion as well as for final development of stable plugs. Primary interfaces for interactions are plasma membrane proteins, of which many have been identified over the past decades in individual studies. However, due to their enucleate structure, platelets are not accessible to large-scale genomic screens and  ...[more]

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