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A quantitative proteomics design for systematic identification of protease cleavage events.

ABSTRACT: Recombinant mouse cathepsin D was added to lysates of mouse dendritic cells. Neo-N-terminal peptides were isolated by N-terminal COFRADIC and their presence in ratios distributed distinct from other peptides was induced by mixing light and heavy labeled proteins according to a novel quantitative design.

INSTRUMENT(S): LTQ Orbitrap, instrument model

ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse)

SUBMITTER: Francis Impens

PROVIDER: PRD000281 | Pride | 2010-08-03

REPOSITORIES: Pride

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			Action	DRS
	PRIDE_Exp_Complete_Ac_13337.pride.mgf.gz	Mgf
	PRIDE_Exp_Complete_Ac_13337.pride.mztab.gz	Mztab
	PRIDE_Exp_Complete_Ac_13337.xml.gz	Xml
	PRIDE_Exp_Complete_Ac_13338.pride.mgf.gz	Mgf
	PRIDE_Exp_Complete_Ac_13338.pride.mztab.gz	Mztab

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