Phosphoprojekt - Comparison of Alternative MS/MS and Bioinformatics Approaches for Confident Phosphorylation Site Localization
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Bruker Daltonics HCT Series, instrument model
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: 
Martin Eisenacher
PROVIDER: PRD000284 | Pride | 2014-03-26
REPOSITORIES: pride
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Publications
Comparison of alternative MS/MS and bioinformatics approaches for confident phosphorylation site localization.
Wiese Heike H Kuhlmann Katja K Wiese Sebastian S Stoepel Nadine S NS Pawlas Magdalena M Meyer Helmut E HE Stephan Christian C Eisenacher Martin M Drepper Friedel F Warscheid Bettina B
Journal of proteome research 20140103 2
Over the past years, phosphoproteomics has advanced to a prime tool in signaling research. Since then, an enormous amount of information about in vivo protein phosphorylation events has been collected providing a treasure trove for gaining a better understanding of the molecular processes involved in cell signaling. Yet, we still face the problem of how to achieve correct modification site localization. Here we use alternative fragmentation and different bioinformatics approaches for the identif ...[more]
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