Dataset Information

Mitochondrial S-NO modified proteins

ABSTRACT: Biotin switch of in vitro S-NO modified rat cardiac mitochondria

INSTRUMENT(S): instrument model, LTQ

ORGANISM(S): Rattus Norvegicus (rat)

TISSUE(S): Heart Ventricle

SUBMITTER: Christopher Murray

PROVIDER: PRD000825 | Pride | 2011-02-21

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	PRIDE_Exp_Complete_Ac_13087.pride.mgf.gz	Mgf
	PRIDE_Exp_Complete_Ac_13087.pride.mztab.gz	Mztab
	PRIDE_Exp_Complete_Ac_13087.xml.gz	Xml
	PRIDE_Exp_Complete_Ac_13088.pride.mgf.gz	Mgf
	PRIDE_Exp_Complete_Ac_13088.pride.mztab.gz	Mztab

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Publications

Site-mapping of in vitro S-nitrosation in cardiac mitochondria: implications for cardioprotection.

Murray Christopher I CI Kane Lesley A LA Uhrigshardt Helge H Wang Sheng-Bing SB Van Eyk Jennifer E JE

Molecular & cellular proteomics : MCP 20101029 3

S-nitrosation (SNO) of mitochondrial protein cysteines can be cardioprotective. Several targets have been implicated, yet the scope and identification of specific residues has not been fully assessed. To address this, a comprehensive assessment of mitochondrial SNO-modifiable cysteines was performed to determine nitric oxide (NO) susceptible pathways and identify novel mechanisms of oxidative cardioprotection. The biotin switch assay and mass spectrometry were used on rat cardiac mitochondrial l ...[more]

PMID: 21036925

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