Ontology highlight
ABSTRACT:
INSTRUMENT(S): Synapt MS
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Hippocampus
SUBMITTER: Ute Distler
LAB HEAD: Ute Distler
PROVIDER: PXD000590 | Pride | 2014-09-25
REPOSITORIES: Pride
Action | DRS | |||
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Distler_et_al_peptide_report_fractions.xlsx | Xlsx | |||
Distler_et_al_protein_report_fractions.xlsx | Xlsx | |||
P2-A1.raw.zip | Raw | |||
P2-A2.raw.zip | Raw | |||
P2-A3.raw.zip | Raw |
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Distler Ute U Schmeisser Michael J MJ Pelosi Assunta A Reim Dominik D Kuharev Jörg J Weiczner Roland R Baumgart Jan J Boeckers Tobias M TM Nitsch Robert R Vogt Johannes J Tenzer Stefan S
Proteomics 20141018 21-22
Located at neuronal terminals, the postsynaptic density (PSD) is a highly complex network of cytoskeletal scaffolding and signaling proteins responsible for the transduction and modulation of glutamatergic signaling between neurons. Using ion-mobility enhanced data-independent label-free LC-MS/MS, we established a reference proteome of crude synaptosomes, synaptic junctions, and PSD derived from mouse hippocampus including TOP3-based absolute quantification values for identified proteins. The fi ...[more]