Proteomics

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Male infertility G. fossarum - While numerous examples of male reproductive disorders have been reported in vertebrates, invertebrate’s organisms have been considerably less studied, despite their ecological importance


ABSTRACT: While numerous examples of male reproductive disorders have been reported in vertebrates, invertebrate’s organisms have been considerably less studied, despite their ecological importance. The aim of this study is to investigate male infertility in the amphipod Gammarus fossarum, a sentinel species in freshwater risk assessment. Thus in laboratory, we exposed male gammarids to different concentrations of three different xenobiotics: cadmium, and two potent arthropods endocrine-disruptor chemicals, methoxyfenozide and pyriproxyfen. Afterward, we investigated alterations of reproductive health by sperm quality markers and proteomes dynamics on the male reproductive tissue by nanoLC-MS/MS for evidencing proteins modulated by toxic exposure.

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Gammarus Fossarum

TISSUE(S): Testis

SUBMITTER: Jean ARMENGAUD  

LAB HEAD: Jean Armengaud

PROVIDER: PXD001267 | Pride | 2014-11-04

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
Cd-C1-S2_1.RAW Raw
Cd-C1-S2_1.mgf Mgf
Cd-C1-S2_1.pride.mgf.gz Mgf
Cd-C1-S2_2.RAW Raw
Cd-C1-S2_2.mgf Mgf
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