Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Velos, LTQ Orbitrap Elite
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Multipotent Stem Cell, Stem Cell, Cell Culture
SUBMITTER: Jon Humphries
LAB HEAD: Martin J Humphries
PROVIDER: PXD001809 | Pride | 2015-07-20
REPOSITORIES: Pride
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20110527FN.zip | Other | |||
20110527PDL.zip | Other | |||
20110706FN.zip | Other | |||
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20110928_JA_MSCFN.zip | Other |
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Proteomics. Clinical applications 20150917 1
<h4>Purpose</h4>Multipotent mesenchymal stem cells (MSCs) have the capability to differentiate down adipocyte, osteocyte and chondrocyte lineages and as such offer a range of potential therapeutic applications. The composition and stiffness of the extracellular matrix (ECM) environment that surrounds cells dictates their transcriptional programme, thereby affecting stem cell lineage decision-making. Cells sense force via linkages between themselves and their microenvironment, and this is transmi ...[more]