Proteomics

Dataset Information

0

Human Hepatocyte Proteome - In-depth quantitative analysis and comparison of the human hepatocyte and hepatoma cell line HepG2 proteomes


ABSTRACT: Here we report a comprehensive proteomic analysis of purified human hepatocytes and a human hepatoma cell line HepG2. The complete dataset comprises 9,400 proteins and provides quantitative depiction of the proteomes of hepatocytes and HepG2 cells at the protein titer and copy number dimensions.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Hepatocyte, Liver

SUBMITTER: Mario Oroshi  

LAB HEAD: Wisniewski Jacek R.

PROVIDER: PXD001874 | Pride | 2016-01-26

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
20120814_EXQ4_JRW_SA_B21_0_L1.raw Raw
20120814_EXQ4_JRW_SA_B21_0_L2.raw Raw
20120814_EXQ4_JRW_SA_B21_0_L3.raw Raw
20120814_EXQ4_JRW_SA_B21_0_L4.raw Raw
20120814_EXQ4_JRW_SA_B21_0_T1.raw Raw
Items per page:
1 - 5 of 124
altmetric image

Publications

In-depth quantitative analysis and comparison of the human hepatocyte and hepatoma cell line HepG2 proteomes.

Wiśniewski Jacek R JR   Vildhede Anna A   Norén Agneta A   Artursson Per P  

Journal of proteomics 20160126


Hepatocytes play a pivotal role in human homeostasis. They are essential in regulation of glucose and lipid levels in blood and play a central role in metabolism of amino acids, lipids, drugs and xenobiotic-compounds. In addition, hepatocytes produce a major portion of proteins circulating in the blood. Hepatocytes were isolated from liver tissue obtained from surgical resections. Proteins were extracted and processed using filter aided sample preparation protocol and were analyzed by LC-MS/MS u  ...[more]

Similar Datasets

2016-03-07 | MSV000079562 | MassIVE
2022-11-01 | GSE206116 | GEO
| PRJNA552265 | ENA
2010-06-21 | E-GEOD-18494 | biostudies-arrayexpress
| PRJNA788285 | ENA
2022-04-04 | E-MTAB-11486 | biostudies-arrayexpress
2018-12-19 | GSE122660 | GEO
2009-10-09 | GSE18494 | GEO
2024-12-10 | GSE190736 | GEO
2024-09-02 | E-MTAB-13852 | biostudies-arrayexpress