Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Cell Culture
DISEASE(S): Disease Free
SUBMITTER: Qiang Zhang
LAB HEAD: Qiang Zhang
PROVIDER: PXD002121 | Pride | 2015-11-23
REPOSITORIES: Pride
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Cundiff Judy K JK McConnell Elizabeth J EJ Lohe Kimberly J KJ Maria Sarah D SD McMahon Robert J RJ Zhang Qiang Q
Journal of proteome research 20151215 1
Mass spectrometry (MS)-based proteomic approaches have largely facilitated our systemic understanding of cellular processes and biological functions. Cutoffs in protein expression fold changes (FCs) are often arbitrarily determined in MS-based quantification with no demonstrable determination of small magnitude changes in protein expression. Therefore, many biological insights may remain veiled due to high FC cutoffs. Herein, we employ the intestinal epithelial cell (IEC) line Caco-2 as a model ...[more]