Proteomics

Dataset Information

0

Mammalian Bcnt/Cfdp1, a potential epigenetic factor characterized by an acidic stretch in the disordered N-terminal and S250 phosphorylation in the conserved C-terminal regions


ABSTRACT: The function of mammalian Bcnt protein is poorly understood yet, though Bcnt homologs (yeast Swc5 and Dorsophila Yeti) play crucial roles in chromatin remodeling organization. In this study, we found that mammalian Bcnt protein shows unusual mobility on SDS-PAGE and is acetylated in vitro by CREB-binding protein. Therefore, we analyzed Bcnt protein by LC-MSMS to characterize the protein structure containing post-translational modifications (phosphorylation and acetylation) which may be the cause of this unusual mobility.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Takehiro Suzuki  

LAB HEAD: Takehiro Suzuki

PROVIDER: PXD002228 | Pride | 2015-06-25

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
Bcnt_AspN_vitro_acetyl.raw Raw
Bcnt_AspN_vivo_phospho1.raw Raw
Bcnt_AspN_vivo_phospho2.raw Raw
Bcnt_AspN_vivo_phospho3.raw Raw
Bcnt_AspN_vivo_phospho4.raw Raw
Items per page:
1 - 5 of 18

Similar Datasets

2017-03-29 | MSV000080755 | MassIVE
2023-09-13 | PXD034992 | Pride
2016-12-23 | PXD000551 | Pride
2023-06-08 | PXD039392 | Pride
2022-07-12 | PXD030601 | Pride
2018-01-10 | PXD006638 | Pride
2022-02-15 | PXD019999 | Pride
2015-04-07 | E-GEOD-60885 | biostudies-arrayexpress
2015-08-01 | E-MTAB-3644 | biostudies-arrayexpress
2016-01-04 | E-MTAB-3923 | biostudies-arrayexpress