Dataset Information

EBV proteomics data - Identification of Epstein-Barr Virus Replication Proteins in Burkitt's Lymphoma Cells

ABSTRACT: A SILAC based experiment of cells infected or uninfected with EBV

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): B Cell

DISEASE(S): Epstein-barr Virus Infectious Disease

SUBMITTER: David Matthews

LAB HEAD: David Matthews

PROVIDER: PXD002461 | Pride | 2015-11-06

REPOSITORIES: Pride

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Publications

Identification of Epstein-Barr Virus Replication Proteins in Burkitt's Lymphoma Cells.

Traylen Chris C Ramasubramanyan Sharada S Zuo Jianmin J Rowe Martin M Almohammad Rajaei R Heesom Kate K Sweet Steve M M SM Matthews David A DA Sinclair Alison J AJ

Pathogens (Basel, Switzerland) 20151029 4

The working model to describe the mechanisms used to replicate the cancer-associated virus Epstein-Barr virus (EBV) is partly derived from comparisons with other members of the Herpes virus family. Many genes within the EBV genome are homologous across the herpes virus family. Published transcriptome data for the EBV genome during its lytic replication cycle show extensive transcription, but the identification of the proteins is limited. We have taken a global proteomics approach to identify vir ...[more]

PMID: 26529022

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