Name: Analysis of differentially expressed proteins in Yersinia enterocolitica-infected HeLa cells
Keywords: Yersinia enterocolitica infection

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Analysis of differentially expressed proteins in Yersinia enterocolitica-infected HeLa cells

ABSTRACT: The purpose of our study was to fill this knowledge gap and to characterize the epithelial cell response to Yersinia enterocolitica infection by label-free proteomic quantification.

INSTRUMENT(S): LTQ

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell

DISEASE(S): Yersinia Enterocolitica Intestinal Infectious Disease

SUBMITTER: Mariola Edelmann

LAB HEAD: Mariola J. Edelmann

PROVIDER: PXD002634 | Pride | 2022-02-22

REPOSITORIES: Pride

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Analysis of differentially expressed proteins in Yersinia enterocolitica-infected HeLa cells.

Alugubelly Navatha N Hercik Kamil K Kibler Peter P Nanduri Bindu B Edelmann Mariola J MJ

Biochimica et biophysica acta 20160205 5

Yersinia enterocolitica is a facultative intracellular pathogen and a causative agent of yersiniosis, which can be contracted by ingestion of contaminated food. Yersinia secretes virulence factors to subvert critical pathways in the host cell. In this study we utilized shotgun label-free proteomics to study differential protein expression in epithelial cells infected with Y.enterocolitica. We identified a total of 551 proteins, amongst which 42 were downregulated (including Prostaglandin E Synth ...[more]

PMID: 26854600

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