Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Erythrocyte, Blood
DISEASE(S): Disease Free
SUBMITTER: Matthew Wither
LAB HEAD: Angelo D'Alessandro
PROVIDER: PXD002798 | Pride | 2015-10-05
REPOSITORIES: Pride
Items per page: 5 1 - 5 of 73 |
Wither Matthew M Dzieciatkowska Monika M Nemkov Travis T Strop Pavel P D'Alessandro Angelo A Hansen Kirk C KC
Transfusion 20151001 2
<h4>Background</h4>Routine storage of red blood cells (RBCs) results in the progressive accumulation of storage lesions. While the clinical relevance of these lesions is still a matter of debate, alterations to RBC morphology and biochemistry, especially in terms of energy and redox homeostasis, are likely to affect RBC physiology and functionality at a minimum. Identification of oxidative modifications that accumulate on key RBC proteins will help bridge the gap between storage induced alterati ...[more]