Proteomics

Dataset Information

0

Changes over lactation in breast milk serum proteins.


ABSTRACT: The objective of this study is to investigate the changes of the breast milk proteome from four individual mothers over a six month lactation period by shotgun proteomic techniques, because a comprehensive understanding of the human milk proteome may lead to better understanding of the needs of infants. This may contribute to the improvement of infant formula.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Milk

SUBMITTER: Sjef Boeren  

LAB HEAD: Sjef Boeren

PROVIDER: PXD003465 | Pride | 2016-02-12

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
LZ181_Mother2_week1.raw Raw
LZ182_Mother2_week2.raw Raw
LZ183_Mother2_week3.raw Raw
LZ184_Mother2_week4.raw Raw
LZ185_Mother2_week8.raw Raw
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Publications

Changes over lactation in breast milk serum proteins involved in the maturation of immune and digestive system of the infant.

Zhang Lina L   de Waard Marita M   Verheijen Hester H   Boeren Sjef S   Hageman Jos A JA   van Hooijdonk Toon T   Vervoort Jacques J   van Goudoever Johannes B JB   Hettinga Kasper K  

Data in brief 20160227


Here we provide data from shot-gun proteomics, using filtered-aided sample preparation (FASP), dimethyl labeling and LC-MS/MS, to quantify the changes in the repertoire of human milk proteins over lactation. Milk serum proteins were analyzed at week 1, 2, 3 4, 8, 16, and 24 in milk from four individual mothers. A total of 247 proteins were identified, of which 200 proteins were quantified. The data supplied in this article supports the accompanying publication (Zhang et al., 2006) [1]. The mass  ...[more]

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