Ontology highlight
ABSTRACT:
INSTRUMENT(S): maXis
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Cell Culture
DISEASE(S): Malignant Neoplasm Of Ovary
SUBMITTER: Georgia Arentz
LAB HEAD: Peter Hoffmann
PROVIDER: PXD003547 | Pride | 2016-09-27
REPOSITORIES: Pride
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IEF_1.baf | Other | |||
IEF_10.baf | Other | |||
IEF_11.baf | Other | |||
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IEF_13.baf | Other |
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Weiland Florian F Arentz Georgia G Klingler-Hoffmann Manuela M McCarthy Peter P Lokman Noor A NA Kaur Gurjeet G Oehler Martin K MK Hoffmann Peter P
Journal of proteome research 20160919 11
Although acetylation is regarded as a common protein modification, a detailed proteome-wide profile of this post-translational modification may reveal important biological insight regarding differential acetylation of individual proteins. Here we optimized a novel peptide IEF fractionation method for use prior to LC-MS/MS analysis to obtain a more in depth coverage of N-terminally acetylated proteins from complex samples. Application of the method to the analysis of the serous ovarian cancer cel ...[more]