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Reticulocytes vs mature red blood cell

ABSTRACT: comparative study reticulocytes vs mature red blood cell

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Cell, Blood

DISEASE(S): Plasmodium Falciparum Malaria

SUBMITTER: Siu Kwan Sze

LAB HEAD: Newman Sze

PROVIDER: PXD003851 | Pride | 2017-11-09

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	141221_Park_iTRAQ_08_A.raw	Raw
	141221_Park_iTRAQ_08_B.raw	Raw
	141221_Park_iTRAQ_08_C.raw	Raw
	141221_Park_iTRAQ_09_A.raw	Raw
	141221_Park_iTRAQ_09_B.raw	Raw

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1 - 5 of 54

Publications

Quantitative mass spectrometry of human reticulocytes reveal proteome-wide modifications during maturation.

Chu Trang T T TTT Sinha Ameya A Malleret Benoit B Suwanarusk Rossarin R Park Jung E JE Naidu Renugah R Das Rupambika R Dutta Bamaprasad B Ong Seow Theng ST Verma Navin K NK Chan Jerry K JK Nosten François F Rénia Laurent L Sze Siu K SK Russell Bruce B Chandramohanadas Rajesh R

British journal of haematology 20171102 1

Erythropoiesis is marked by progressive changes in morphological, biochemical and mechanical properties of erythroid precursors to generate red blood cells (RBC). The earliest enucleated forms derived in this process, known as reticulocytes, are multi-lobular and spherical. As reticulocytes mature, they undergo a series of dynamic cytoskeletal re-arrangements and the expulsion of residual organelles, resulting in highly deformable biconcave RBCs (normocytes). To understand the significant, yet n ...[more]

PMID: 29094334

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