Dataset Information
Molecular characterization of HUVEC in vivo and in vitro
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: 
Hannes Hahne
LAB HEAD: Hannes Hahne
PROVIDER: PXD003975 | Pride | 2017-06-26
REPOSITORIES: Pride
Dataset's files
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Publications
Bacterial Cellulose Shifts Transcriptome and Proteome of Cultured Endothelial Cells Towards Native Differentiation.
Molecular & cellular proteomics : MCP 20170621 9
Preserving the native phenotype of primary cells <i>in vitro</i> is a complex challenge. Recently, hydrogel-based cellular matrices have evolved as alternatives to conventional cell culture techniques. We developed a bacterial cellulose-based aqueous gel-like biomaterial, dubbed Xellulin, which mimics a cellular microenvironment and seems to maintain the native phenotype of cultured and primary cells. When applied to human umbilical vein endothelial cells (HUVEC), it allowed the continuous culti ...[more]
