P falciparum gametocyte proteomes
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Plasmodium Falciparum (isolate 3d7)
TISSUE(S): Blood Cell, Blood
DISEASE(S): Plasmodium Falciparum Malaria
SUBMITTER: 
Edwin Lasonder
LAB HEAD: Edwin Lasonder
PROVIDER: PXD004124 | Pride | 2016-07-21
REPOSITORIES: Pride
Dataset's files
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Publications
Comparative Proteomics and Functional Analysis Reveal a Role of Plasmodium falciparum Osmiophilic Bodies in Malaria Parasite Transmission.
Suárez-Cortés Pablo P Sharma Vikram V Bertuccini Lucia L Costa Giulia G Bannerman Naa-Lamiley NL Sannella Anna Rosa AR Sannella Anna Rosa AR Williamson Kim K Klemba Michael M Levashina Elena A EA Lasonder Edwin E Alano Pietro P
Molecular & cellular proteomics : MCP 20160718 10
An essential step in the transmission of the malaria parasite to the Anopheles vector is the transformation of the mature gametocytes into gametes in the mosquito gut, where they egress from the erythrocytes and mate to produce a zygote, which matures into a motile ookinete. Osmiophilic bodies are electron dense secretory organelles of the female gametocytes which discharge their contents during gamete formation, suggestive of a role in gamete egress. Only one protein with no functional annotati ...[more]
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