Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Cell Culture
DISEASE(S): Breast Cancer
SUBMITTER: Brock Conley
LAB HEAD: Professor Roger Daly
PROVIDER: PXD004250 | Pride | 2016-08-24
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
MaxQuantOutput.tar.gz | Other | |||
ZC20140815_DSR_1.raw | Raw | |||
ZC20140815_DSR_2.raw | Raw | |||
ZC20140815_DSR_3.raw | Raw | |||
ZC20140815_SGK_1.raw | Raw |
Items per page: 5 1 - 5 of 7 |
Liu Ling L Phua Yu Wei YW Lee Rachel S RS Ma Xiuquan X Jenkins Yiping Y Novy Karel K Humphrey Emily S ES Chan Howard H Shearer Robert R Ong Poh Chee PC Dai Weiwen W Saunders Darren N DN Lucet Isabelle S IS Daly Roger J RJ
The Journal of biological chemistry 20160816 41
SgK269/PEAK1 is a pseudokinase and scaffolding protein that plays a critical role in regulating growth factor receptor signal output and is implicated in the progression of several cancers, including those of the breast, colon, and pancreas. SgK269 is structurally related to SgK223, a human pseudokinase that also functions as a scaffold but recruits a distinct repertoire of signaling proteins compared with SgK269. Structural similarities between SgK269 and SgK223 include a predicted α-helical re ...[more]