Proteomics

Dataset Information

0

Proteomics of human dendritic cell subsets


ABSTRACT: We exploited label-free quantitative mass spectrometry to compare primary human blood Dendritic cells (DCs) subsets protein expression to identify new markers. Subsets distinguished are: Plasmacytoid DCs (pDC) and BDCA3+ and CD1c+ myeloid DCs and CD16+ monocytes. The dendritic cells were analyzed by LC-MS/MS and processed by MaxQuant for identification and LFQ quantification.

INSTRUMENT(S): LTQ FT

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Dendritic Cell, Blood

SUBMITTER: Kuntal worah  

LAB HEAD: Edwin Lasonder

PROVIDER: PXD004678 | Pride | 2016-09-27

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
20110303EL01.RAW Raw
20110303EL02.RAW Raw
20110303EL03.RAW Raw
20110303EL04.RAW Raw
20110303EL05.RAW Raw
Items per page:
1 - 5 of 726
altmetric image

Publications


Dendritic cells (DCs) play a key role in orchestrating adaptive immune responses. In human blood, three distinct subsets exist: plasmacytoid DCs (pDCs) and BDCA3+ and CD1c+ myeloid DCs. In addition, a DC-like CD16+ monocyte has been reported. Although RNA-expression profiles have been previously compared, protein expression data may provide a different picture. Here, we exploited label-free quantitative mass spectrometry to compare and identify differences in primary human DC subset proteins. Mo  ...[more]

Similar Datasets

2013-12-21 | E-GEOD-42860 | biostudies-arrayexpress
2008-01-24 | GSE9810 | GEO
2008-06-16 | E-GEOD-9810 | biostudies-arrayexpress
2018-10-21 | GSE121544 | GEO
2018-10-20 | GSE121446 | GEO
2010-10-04 | E-GEOD-22432 | biostudies-arrayexpress
2015-06-26 | E-GEOD-54120 | biostudies-arrayexpress
2013-09-30 | E-GEOD-43169 | biostudies-arrayexpress
2010-09-10 | E-MTAB-186 | biostudies-arrayexpress
2022-02-16 | GSE193733 | GEO