Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ FT
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Dendritic Cell, Blood
SUBMITTER: Kuntal worah
LAB HEAD: Edwin Lasonder
PROVIDER: PXD004678 | Pride | 2016-09-27
REPOSITORIES: Pride
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Worah Kuntal K Mathan Till S M TSM Vu Manh Thien Phong TP Keerthikumar Shivakumar S Schreibelt Gerty G Tel Jurjen J Duiveman-de Boer Tjitske T Sköld Annette E AE van Spriel Annemiek B AB de Vries I Jolanda M IJM Huynen Martijn A MA Wessels Hans J HJ Gloerich Jolein J Dalod Marc M Lasonder Edwin E Figdor Carl G CG Buschow Sonja I SI
Cell reports 20160901 11
Dendritic cells (DCs) play a key role in orchestrating adaptive immune responses. In human blood, three distinct subsets exist: plasmacytoid DCs (pDCs) and BDCA3+ and CD1c+ myeloid DCs. In addition, a DC-like CD16+ monocyte has been reported. Although RNA-expression profiles have been previously compared, protein expression data may provide a different picture. Here, we exploited label-free quantitative mass spectrometry to compare and identify differences in primary human DC subset proteins. Mo ...[more]