Proteomics

Dataset Information

0

Interactomes of neural cell adhesion molecule 1 and the metal ion transporter ZIP6 in mouse NMuMG epithelial cells with transforming growth factor beta 1-induced fibroblastoid morphology


ABSTRACT: The prion protein (PrP) evolved from the subbranch of ZIP metal ion transporters comprising ZIPs 5, 6 and 10, raising the prospect that the study of these ZIPs may reveal insights relevant for understanding PrP function. PrP and ZIP6 are required for the execution of a cellular program known as epithelial-to-mesenchymal transition (EMT). Polysialylation of neural cell adhesion molecule 1 (NCAM1) during EMT is also controlled by PrP. Here we report the ZIP6 interactome and ZIP6-dependent NCAM1 interactome in a mouse cell EMT model.

INSTRUMENT(S): Orbitrap Fusion ETD

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Epithelial Cell, Cell Culture

DISEASE(S): Disease Free

SUBMITTER: Declan Williams  

LAB HEAD: Gerold Schmitt-Ulms

PROVIDER: PXD004685 | Pride | 2017-02-13

REPOSITORIES: Pride

Similar Datasets

2016-06-01 | PXD003398 | Pride
2018-05-24 | PXD008781 | Pride
2016-07-03 | E-GEOD-72952 | biostudies-arrayexpress
2015-07-10 | PXD001875 | Pride
2014-11-19 | PXD001301 | Pride
2015-11-01 | E-GEOD-57233 | biostudies-arrayexpress
2021-11-02 | PXD024870 | Pride
2019-11-13 | PXD010040 | Pride
2016-04-01 | E-GEOD-78502 | biostudies-arrayexpress
2014-09-09 | E-GEOD-61217 | biostudies-arrayexpress