Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)
SUBMITTER: Oded Kleifeld
LAB HEAD: Gali Prag
PROVIDER: PXD004761 | Pride | 2018-10-26
REPOSITORIES: Pride
Items per page: 5 1 - 5 of 14 |
Keren-Kaplan Tal T Zeev Peters Lee L Levin-Kravets Olga O Attali Ilan I Kleifeld Oded O Shohat Noa N Artzi Shay S Zucker Ori O Pilzer Inbar I Reis Noa N Glickman Michael H MH Ben-Aroya Shay S Prag Gali G
Nature communications 20161004
Ubiquitin receptors decode ubiquitin signals into many cellular responses. Ubiquitin receptors also undergo coupled monoubiquitylation, and rapid deubiquitylation has hampered the characterization of the ubiquitylated state. Using bacteria that express a ubiquitylation apparatus, we purified and determined the crystal structure of the proteasomal ubiquitin-receptor Rpn10 in its ubiquitylated state. The structure shows a novel ubiquitin-binding patch that directs K84 ubiquitylation. Superimpositi ...[more]