Dataset Information

PROTEOMIC PROFILING OF EXTRACELLULAR VESICLES OBTAINED FROM Toxoplasma gondii AND TOXOPLASMA-INFECTED CELLS

ABSTRACT: Here, we purified T. gondii obtained from human foreskin fibroblast (HFF) infected cells and performed the first comprehensive proteomic profiling of the extracellular vesicles secreted by these parasites.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Homo Sapiens (human) Toxoplasma Gondii

TISSUE(S): Cell Culture, Fibroblast

DISEASE(S): Toxoplasmosis

SUBMITTER: Paulo Carvalho

LAB HEAD: Patricia Morking

PROVIDER: PXD004895 | Pride | 2017-06-26

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	20141031_PM_MvToxo1_1.RAW	Raw
	20141031_PM_MvToxo1_1.sqt	Other
	20141031_PM_MvToxo1_2.RAW	Raw
	20141031_PM_MvToxo1_2.sqt	Other
	20141031_PM_MvToxo1_3.RAW	Raw

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Publications

Proteomic profiling of extracellular vesicles secreted from Toxoplasma gondii.

Wowk Pryscilla Fanini PF Zardo Maria Luisa ML Miot Halisson Tesseroli HT Goldenberg Samuel S Carvalho Paulo Costa PC Mörking Patricia Alves PA

Proteomics 20170718 15-16

Toxoplasma gondii infects a wide range of hosts worldwide, including humans and domesticated animals causing toxoplasmosis disease. Recently, exosomes, small extracellular vesicles (EV) that contain nucleic acids, proteins, and lipids derived from their original cells were linked with disease protection. The effect of EVs derived from T. gondii on the immune response and its relevance in a physiological context is unknown. Here we disclose the first proteomic profiling of T. gondii EVs compared ...[more]

PMID: 28643940

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