Proteomics

Dataset Information

0

ATPase activity in Plasmodium falciparum asexual blood stages and gametocytes


ABSTRACT: Characterization of ATPase activity associated with gametocytogenesis in P. falciparum

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Plasmodium Falciparum

SUBMITTER: Matthew Monroe  

LAB HEAD: Aaron Wright

PROVIDER: PXD005335 | Pride | 2017-10-31

REPOSITORIES: Pride

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Publications


Effective malaria control and elimination in hyperendemic areas of the world will require treatment of the <i>Plasmodium falciparum</i> (<i>Pf</i>) blood stage that causes disease as well as the gametocyte stage that is required for transmission from humans to the mosquito vector. Most currently used therapies do not kill gametocytes, a highly specialized, non-replicating sexual parasite stage. Further confounding next generation drug development against <i>Pf</i> is the unknown metabolic state  ...[more]

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