Ribosome Profiling in P. falciparum asexual blood stages
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ABSTRACT: The description of the transcriptome and proteome datasets of Plasmodium falciparum, the deadliest strain of human malaria, has been a tremendous resource for the understanding of the molecular physiology of this parasite. However, the underlying translational control that links global measurements of steady-state mRNA with protein levels is not well understood. Our work bridges this disconnect by measuring translation on a whole genome scale using ribosome profiling, providing the first measurements of new protein synthesis through the asexual blood phase developmental cycle.
ORGANISM(S): Plasmodium falciparum
PROVIDER: GSE58402 | GEO | 2014/12/01
SECONDARY ACCESSION(S): PRJNA252511
REPOSITORIES: GEO
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