Transcriptomics

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Ribosome Profiling in P. falciparum asexual blood stages


ABSTRACT: The description of the transcriptome and proteome datasets of Plasmodium falciparum, the deadliest strain of human malaria, has been a tremendous resource for the understanding of the molecular physiology of this parasite. However, the underlying translational control that links global measurements of steady-state mRNA with protein levels is not well understood. Our work bridges this disconnect by measuring translation on a whole genome scale using ribosome profiling, providing the first measurements of new protein synthesis through the asexual blood phase developmental cycle.

ORGANISM(S): Plasmodium falciparum

PROVIDER: GSE58402 | GEO | 2014/12/01

SECONDARY ACCESSION(S): PRJNA252511

REPOSITORIES: GEO

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