Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Permanent Cell Line Cell, Cell Culture
DISEASE(S): Brain Glioblastoma Multiforme
SUBMITTER: Kangling Zhang
LAB HEAD: Kangling Zhang
PROVIDER: PXD005487 | Pride | 2017-09-12
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
U87_Hypoxia_Exp1.msf | Msf | |||
U87_Hypoxia_Exp1.zip | Other | |||
U87_Hypoxia_Exp2.msf | Msf | |||
U87_Hypoxia_Exp2.zip | Other |
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Molecular & cellular proteomics : MCP 20170905 11
Rapidly proliferating tumors are exposed to a hypoxic microenvironment because of their density, high metabolic consumption, and interruptions in blood flow because of immature angiogenesis. Cellular responses to hypoxia promote highly malignant and metastatic behavior, as well as a chemotherapy-resistant state. To better understand the complex relationships between hypoxic adaptations and cancer progression, we studied the dynamic proteome responses of glioblastoma cells exposed to hypoxia via ...[more]