Dataset Information

Striatal and hippocampal astrocyte proteomes

ABSTRACT: We quantitavely compared striatal and hippocampal astrocyte proteomes using stable-isotopic dimethyl labeling.

OTHER RELATED OMICS DATASETS IN: PRJNA363047

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Brain, T Cell, Astrocyte

SUBMITTER: Blanca Diaz Castro

LAB HEAD: Baljit S. Khakh

PROVIDER: PXD005852 | Pride | 2017-07-10

REPOSITORIES: Pride

ACCESS DATA

Dataset's files

Source:

			Action	DRS
	GFP_Uniprot_mus_musculus_10090_v2015.05_caniso.fasta	Fasta
	Replicate1All_Fractions_LStrMHip.msf	Msf
	Replicate1All_Fractions_LStrMHip.mzid	Mzid
	Replicate1All_Fractions_LStrMHip.txt	Txt
	Replicate1_Fraction10_LStrMHip.RAW	Raw

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Publications

Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence.

Chai Hua H Diaz-Castro Blanca B Shigetomi Eiji E Monte Emma E Octeau J Christopher JC Yu Xinzhu X Cohn Whitaker W Rajendran Pradeep S PS Vondriska Thomas M TM Whitelegge Julian P JP Coppola Giovanni G Khakh Baljit S BS

Neuron 20170714 3

Astrocytes are ubiquitous in the brain and are widely held to be largely identical. However, this view has not been fully tested, and the possibility that astrocytes are neural circuit specialized remains largely unexplored. Here, we used multiple integrated approaches, including RNA sequencing (RNA-seq), mass spectrometry, electrophysiology, immunohistochemistry, serial block-face-scanning electron microscopy, morphological reconstructions, pharmacogenetics, and diffusible dye, calcium, and glu ...[more]

PMID: 28712653

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