Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Cricetulus Griseus (chinese Hamster) (cricetulus Barabensis Griseus)
SUBMITTER: David Plotnik
LAB HEAD: Shiu-Lok Hu
PROVIDER: PXD006061 | Pride | 2017-09-04
REPOSITORIES: Pride
Action | DRS | |||
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20161205_DEAE-Peak1-MW959.mzXML | Mzxml | |||
20161205_DEAE-Peak1-MW959.pep.xml | Pepxml | |||
20161205_DEAE-Peak1-MW959.raw | Raw | |||
CRIGR.fasta.20161205 | Fasta | |||
comet.params | Other |
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Journal of virology 20171013 21
Gut-homing α<sub>4</sub>β<sub>7</sub><sup>high</sup> CD4<sup>+</sup> T lymphocytes have been shown to be preferentially targeted by human immunodeficiency virus type 1 (HIV-1) and are implicated in HIV-1 pathogenesis. Previous studies demonstrated that HIV-1 envelope protein gp120 binds and signals through α<sub>4</sub>β<sub>7</sub> and that this likely contributes to the infection of α<sub>4</sub>β<sub>7</sub><sup>high</sup> T cells and promotes cell-to-cell virus transmission. Structures withi ...[more]