Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Wolbachia Pipientis Wmelcs Aedes Aegypti
TISSUE(S): Midgut
SUBMITTER: Vincent Geoghegan
LAB HEAD: Steven P. Sinkins
PROVIDER: PXD006239 | Pride | 2017-09-19
REPOSITORIES: pride
Action | DRS | |||
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C475_TMT.sf3 | Other | |||
SamplesReportforC475_TMTannotated.xlsx | Xlsx | |||
TMT_10_C475.raw | Raw | |||
TMT_12_5_C475.raw | Raw | |||
TMT_15_C475.raw | Raw |
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Geoghegan Vincent V Stainton Kirsty K Rainey Stephanie M SM Ant Thomas H TH Dowle Adam A AA Larson Tony T Hester Svenja S Charles Philip D PD Thomas Benjamin B Sinkins Steven P SP
Nature communications 20170913 1
Wolbachia are intracellular maternally inherited bacteria that can spread through insect populations and block virus transmission by mosquitoes, providing an important approach to dengue control. To better understand the mechanisms of virus inhibition, we here perform proteomic quantification of the effects of Wolbachia in Aedes aegypti mosquito cells and midgut. Perturbations are observed in vesicular trafficking, lipid metabolism and in the endoplasmic reticulum that could impact viral entry a ...[more]