Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Platelet, Platelet
DISEASE(S): Cardiovascular System Disease
SUBMITTER: Mattias Vesterlund
LAB HEAD: Janne Lehtiö
PROVIDER: PXD006559 | Pride | 2018-01-03
REPOSITORIES: Pride
Items per page: 1 - 5 of 78 |
Scientific reports 20180111 1
Platelet activation triggers thrombus formation in physiological and pathological conditions, such as acute coronary syndromes. Current therapies still fail to prevent thrombotic events in numerous patients, indicating that the mechanisms modulating platelet response during activation need to be clarified. The evidence that platelets are capable of de novo protein synthesis in response to stimuli raised the issue of how megakaryocyte-derived mRNAs are regulated in these anucleate cell fragments. ...[more]