Proteomics

Dataset Information

0

PRM assay for functional tubule proteomics


ABSTRACT: We used a targeted proteomics assay to survey proximal tubule function.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Kidney

SUBMITTER: Markus Rinschen  

LAB HEAD: Markus Rinschen

PROVIDER: PXD006896 | Pride | 2018-06-28

REPOSITORIES: Pride

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Publications


In diseases of many parenchymatous organs, heterogeneous deterioration of individual functional units determines the clinical prognosis. However, the molecular characterization at the level of such individual subunits remains a technological challenge that needs to be addressed in order to better understand pathological mechanisms. Proteinuric glomerular kidney diseases are frequent and assorted diseases affecting a fraction of glomeruli and their draining tubules to variable extents, and for wh  ...[more]

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